Glia – Communicable Diseases Research

Neuroinflammation in Dementia-Therapeutic Directions in a COVID-19 Pandemic Setting

Article

Published on 2022-09-222022-11-15
Journal: Cells
[Category] SARS, 진단,

SARS-CoV-2 spike protein induces cognitive deficit and anxiety-like behavior in mouse via non-cell autonomous hippocampal neuronal death

SARS-CoV-2 스파이크 단백질은 비 세포 자율 해마 신경 세포 죽음을 통해 마우스에서인지 결핍 및 불안과 같은 행동을 유도합니다

Article

Published on 2022-03-312022-09-12
Journal: Scientific Reports
[Category] MERS, SARS, 진단,

SARS-CoV-2 Morbidity in the CNS and the Aged Brain Specific Vulnerability

Review

Published on 2022-03-292023-06-15
Journal: International Journal of Molecular Sciences
[Category] MERS, SARS,

[키워드] aging Brain COVID-19 Glia neurodegeneration SARS-CoV-2
[DOI] 10.3390/ijms23073782 PMC 바로가기 [Article Type] Review

Regulation of gliotoxin biosynthesis and protection in Aspergillus species

아스 페르 길 루스 종에서의 글리 톡신 생합성 및 보호의 조절

Research Article

Published on 2022-01-182022-09-06
Journal: PLoS Genetics
[Category] Communicable Disease,

[키워드] Analysis approach aspergillosis Aspergillus Aspergillus fumigatus Aspergillus oryzae best cause colonisation component conserved disease Disease progression enzyme expresse expression expression of gene expression pattern facilitate fungal Genes genetic determinant genetic determinants Genome Glia homolog homologs human immune response identify Immune cell impair include involved kojic acid mechanism metabolism modulated mycotoxin negative regulation neutralising nidulan nidulans observé occur Occurrence pathogenicity producing regulate required responses RNA-sequencing screened secrete secretion sensitivity significantly sulfur Taking TFS toxic effect toxic effects transcription factor transcription factors transcriptional transcriptional response virulence
[DOI] 10.1371/journal.pgen.1009965 PMC 바로가기 [Article Type] Research Article

Postmortem brain 7T MRI with minimally invasive pathological correlation in deceased COVID-19 subjects

Original Article

Published on 2022-01-152022-10-29
Journal: Insights into Imaging
[Category] COVID-19,

[키워드] abnormality alteration Analysis antibody Autopsy Brain changes in correlation cortical COVID-19 COVID-19 patient COVID-19 patients Critically ill Deceased disease edema effective Encephalitis evaluate feature fixed foci ganglia Glia Hematoxylin and eosin hemorrhage Hemorrhagic histological analysis hypoxia IHC imaging Invasion invasive MIA monoclonal MRI Neuroimaging Neuropathology Other Patient perivascular polymerase chain Postmortem Reactions reactive Result reverse transcription RT-PCR SARS-CoV-2 SARS-CoV-2 RNA Seven small vessel subarachnoid hemorrhage subject tissue vascular ectasia
[DOI] 10.1186/s13244-021-01144-w PMC 바로가기 [Article Type] Original Article

Sequelae and Comorbidities of COVID-19 Manifestations on the Cardiac and the Vascular Systems

Physiology

Published on 2022-01-142022-10-31
Journal: Frontiers in Physiology
[Category] COVID-19,

[키워드] ACE2 ACE2 receptor acute respiratory syndrome age aging angiotensin-converting enzyme 2 cardiac Cardiac arrhythmia cardiac arrhythmias cardiac complication Cardiac complications cardiovascular comorbidities cardiovascular condition cardiovascular disease case fatality rates complications complications of COVID-19 condition conditions coronavirus cough COVID-19 COVID-19 infection COVID-19 patient COVID-19 patients Critical case damaged de novo diabetes dysregulation elderly endothelial cells evaluate expressed expression Fever Glia greater highest Hypercoagulation hypertension improve clinical outcome in-depth analysis incidence include increased risk Infection Interaction ischemic heart disease manifestation mechanism mortality risk Myocardial Myocardial infarction Neuron Neuropathy oxygen supply pandemic Patient patients presenting symptom Prognosis prognostic indicator reduce reported risk risk factor SARS-CoV-2 SARS-COV-2 infection SARS-CoV-2 patient SARS-CoV-2 patients SARS-CoV2 Shortness of breath shown System systemic hyper-inflammation the SARS-CoV-2 tissue vasculature virus
[DOI] 10.3389/fphys.2021.748972 PMC 바로가기 [Article Type] Physiology

Molecular docking of SARS-COV-2 Spike epitope sequences identifies heterodimeric peptide-protein complex formation with human Zo-1, TLR8 and brain specific glial proteins

SARS-COV-2 스파이크 에피토프 서열의 분자 도킹으로 인간 Zo-1, TLR8 및 뇌 특이적 신경교 단백질과의 이종이량체 펩티드-단백질 복합체 형성 확인

Article

Published on 2021-12-012022-09-11
Journal: Medical Hypotheses
[Category] SARS, 유전자 메커니즘,

[키워드] allele asphyxia binding Blood brain barrier blurred vision Brain Brain infection cause clinical observation clinical observations complex death deviation docking epitope epitope peptide Epitopes experiment Glia glial cell headache heterodimeric HLA-DRB1 Human brain human population Hypothesis identify immunogenic induce infect Infection Inflammation Interaction Loss of Smell mechanism modify molecular molecule NDRG2 neurological abnormalities neurological abnormality observation observations peptide peptides performed Protein Proteins question receptor respiratory tract illness RMSD root S100B SARS-CoV-2 SARS-COV-2 infection selected sequence specific protein spike spike epitopes Spike epitopes. Spike protein structures Symptoms tested the Spike TLR TLR8 Toll-like receptor VCAM1 virus working hypothesis zonula zonula occludens
[DOI] 10.1016/j.mehy.2021.110706 PMC 바로가기 [Article Type] Article

Post COVID-19 Syndrome in Patients with Asymptomatic/Mild Form

Review

Published on 2021-10-302022-10-28
Journal: Pathogens
[Category] COVID-19,

Post-viral effects of COVID-19 in the olfactory system and their implications

후각 시스템에 대한 COVID-19의 바이러스 후 영향 및 그 의미

Review

Published on 2021-09-012022-09-12
Journal: The Lancet. Neurology
[Category] 진단,

[키워드] accelerate acute phase Autopsy Brain brain region chemosensory clinical CNS Course COVID-19 Critical disease Effect evaluate Evidence Glia histological histopathological identify impair impairment implication Infection infection control Inflammation Inflammatory knowledge likelihood localised inflammation marker mechanism molecular molecular data nasal neurodegenerative neurodegenerative disorder Neuroimaging neurological Neurological deficit Neurological disease Neuron olfactory olfactory bulb olfactory dysfunction Olfactory epithelium patients with COVID-19 persistent Prevalence prognostic progression provide radiological recent replication of SARS-CoV-2 Research risk SARS-CoV-2 SARS-COV-2 infection small sample size specimen Spread structures subset symptomatic Trial upper respiratory viral infection virus
[DOI] 10.1016/S1474-4422(21)00182-4 PMC 바로가기 [Article Type] Review

Extracellular Vesicles as a Means of Viral Immune Evasion, CNS Invasion, and Glia-Induced Neurodegeneration

Article

Published on 2021-07-052023-08-30
Journal: Frontiers in Cellular Neuroscience
[Category] E형 간염,

[키워드] Astrocyte Exosomes Extracellular vesicles Glia microglia Microvesicles neurodegeneration virus
[DOI] 10.3389/fncel.2021.695899 PMC 바로가기